No, each Babykixx fruit smoothie pouch is pasteurized and does not require refrigeration as long as it remains sealed.
Babykixx is real fruit and tastes great so feel free to throw some in the fridge and enjoy them cool. You can even freeze them. Many first trimester moms have found that frozen things can help reduce morning sickness, give it a try.
Heat accelerates the aging process and may reduce the effectiveness of the nutraceuticals inside the pouch.